Activation of the innate immune response by endogenous retroviruses
نویسندگان
چکیده
منابع مشابه
Activation of the innate immune response by endogenous retroviruses.
The human genome comprises 8 % endogenous retroviruses (ERVs), the majority of which are defective due to deleterious mutations. Nonetheless, transcripts of ERVs are found in most tissues, and these transcripts could either be reverse transcribed to generate ssDNA or expressed to generate proteins. Thus, the expression of ERVs could produce nucleic acids or proteins with viral signatures, much ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2015
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.000017